House of Colonna (Lucrezia Colonna di Stigliano, Colombo, Palazzo, di Paliano, Barberini)
Influence and Power: The Colonna family was one of the most powerful families in Rome during the Renaissance and Baroque periods. They held significant political and ecclesiastical influence and often played a crucial role in papal elections.
Barberini Family: This family produced one pope: Urban VIII.
Mattei: Cardinal Protectors: Members of the Mattei family often held important positions in the Roman Curia, including cardinal protectorates over various religious orders and institutions. Intermarriage with Roman Nobility: The Mattei family frequently intermarried with other prominent Roman families, such as the Colonnas, Orsini, and Gaetani. These alliances helped to consolidate their power and influence within the city.